EdenteV2, Main, Exploration, bibRecord, 001807

Prevalence and Clinical Significance of Supine-Dependent Obstructive Sleep Apnea in Patients Using Oral Appliance Therapy

Identifieur interne : 001807 ( Main/Exploration ); précédent : 001806; suivant : 001808

Prevalence and Clinical Significance of Supine-Dependent Obstructive Sleep Apnea in Patients Using Oral Appliance Therapy

Auteurs : Marijke Dieltjens [Belgique] ; Marc J. Braem [Belgique] ; Paul H. Van De Heyning [Belgique] ; Kristien Wouters [Belgique] ; Olivier M. Vanderveken [Belgique]

Source :

Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine [ 1550-9389 ] ; 2014.

RBID : PMC:4153117

Abstract

Study Objective:

The prevalence of supine-dependent obstructive sleep apnea (sdOSA) in a general population ranges from 20% to 60%, depending on the criteria used. Currently, the prevalence and evolution of sdOSA once oral appliance therapy with a mandibular advancement device (OA_m) has started is unknown. In addition, literature on the correlation between sdOSA and treatment success with OA_m is not unequivocal. The first purpose of this study was to assess the prevalence of sdOSA before and under OA_m therapy. Second, the conversion rate from non-sdOSA to sdOSA during OA_m therapy was evaluated. The third and final goal was to analyze the correlation between sdOSA and treatment success with OA_m therapy in the patient population.

Methods:

Two hundred thirty-seven consecutive patients (age 48 ± 9 years; male/female ratio 173/64; AHI 20.1 ± 14.7 events/h; BMI 27.2 ± 4.3 kg/m²) starting OA_m therapy were included.

Results:

The prevalence of sdOSA before the start of OA_m therapy, ranged from 27.0% to 67.5%. The prevalence of residual sdOSA under OA_m therapy in this study ranged from 17.5% to 33.9%. Second, the conversion rate from non-sdOSA to sdOSA ranged from 23.0% to 37.5%. Third, the presence of sdOSA at baseline was not a significant factor for treatment success with OA_m therapy.

Conclusions:

The results of this study indicate that the prevalence of sdOSA before and under OA_m therapy is relatively high. One-third of patients shift from non-sdOSA to sdOSA. Finally, treatment success for OA_m therapy was not significantly correlated with the presence of sdOSA at baseline.

Citation:

Dieltjens M, Braem MJ, Van de Heyning PH, Wouters K, Vanderveken OM. Prevalence and clinical significance of supine-dependent obstructive sleep apnea in patients using oral appliance therapy. J Clin Sleep Med 2014;10(9):959-964.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153117

DOI: 10.5664/jcsm.4024
PubMed: 25142766
PubMed Central: 4153117

Affiliations:

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<front><div type="abstract" xml:lang="en"><sec><title>Study Objective:</title>
<p>The prevalence of supine-dependent obstructive sleep apnea (sdOSA) in a general population ranges from 20% to 60%, depending on the criteria used. Currently, the prevalence and evolution of sdOSA once oral appliance therapy with a mandibular advancement device (OA<sub>m</sub>
) has started is unknown. In addition, literature on the correlation between sdOSA and treatment success with OA<sub>m</sub>
 is not unequivocal. The first purpose of this study was to assess the prevalence of sdOSA before and under OA<sub>m</sub>
 therapy. Second, the conversion rate from non-sdOSA to sdOSA during OA<sub>m</sub>
 therapy was evaluated. The third and final goal was to analyze the correlation between sdOSA and treatment success with OA<sub>m</sub>
 therapy in the patient population.</p>
</sec>
<sec><title>Methods:</title>
<p>Two hundred thirty-seven consecutive patients (age 48 ± 9 years; male/female ratio 173/64; AHI 20.1 ± 14.7 events/h; BMI 27.2 ± 4.3 kg/m<sup>2</sup>
) starting OA<sub>m</sub>
 therapy were included.</p>
</sec>
<sec><title>Results:</title>
<p>The prevalence of sdOSA before the start of OA<sub>m</sub>
 therapy, ranged from 27.0% to 67.5%. The prevalence of residual sdOSA under OA<sub>m</sub>
 therapy in this study ranged from 17.5% to 33.9%. Second, the conversion rate from non-sdOSA to sdOSA ranged from 23.0% to 37.5%. Third, the presence of sdOSA at baseline was not a significant factor for treatment success with OA<sub>m</sub>
 therapy.</p>
</sec>
<sec><title>Conclusions:</title>
<p>The results of this study indicate that the prevalence of sdOSA before and under OA<sub>m</sub>
 therapy is relatively high. One-third of patients shift from non-sdOSA to sdOSA. Finally, treatment success for OA<sub>m</sub>
 therapy was not significantly correlated with the presence of sdOSA at baseline.</p>
</sec>
<sec><title>Citation:</title>
<p>Dieltjens M, Braem MJ, Van de Heyning PH, Wouters K, Vanderveken OM. Prevalence and clinical significance of supine-dependent obstructive sleep apnea in patients using oral appliance therapy. <italic>J Clin Sleep Med</italic>
 2014;10(9):959-964.</p>
</sec>
</div>
</front>
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Prevalence and Clinical Significance of Supine-Dependent Obstructive Sleep Apnea in Patients Using Oral Appliance Therapy

Prevalence and Clinical Significance of Supine-Dependent Obstructive Sleep Apnea in Patients Using Oral Appliance Therapy

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